biology by bradford · ib biology · b2.2 (hl) · form and function

The endomembrane system

A protein is written in the nucleus and ends up in the membrane. Put the eight steps of that journey back in order, build it in plasticine, then watch it run.

The brief

Read it once, then build the sequence.

Order the steps

Tap a step on the left to place it at the end, or drag any step straight into a numbered slot and the rest shift down to make room. Tap a placed step to send it back.

Steps, out of order

Your sequence

then build it

Model the journey in plasticine

Once your order is checked, make the cell on the desk. One colour per compartment: nucleus, rough ER, Golgi, vesicle, membrane. Then make your protein as a separate piece and physically move it through all eight steps.

The protein has to change as it travels. Show what the Golgi does to it.
Your vesicle must be a container, not a blob. It has to carry the protein and then fuse.
Stop at the membrane and decide: does your protein leave the cell, or stay embedded in it?

Be ready to talk through your model. If a step cannot be shown with the plasticine, that is the step to look at again.

Watch it run

Step through the correct sequence. The compartment doing the work lights up, the rest fade back.

Press play to follow the protein from gene to membrane.

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