Biology by Bradford
Biology by Bradford · AP Biology · Unit 3.3

Cellular Energy

Order costs something. Every structure a cell maintains is paid for continuously, in a currency it holds only seconds of.

AP · U3.3CED 3.4Interactive lesson
Concept 01 · CED 3.4

A currency, not a savings account

Cells do not run on glucose. They run on ATP — and they hold barely any of it, regenerating the entire pool many times a minute.

The store

Glucose

Dense, stable and transportable. Excellent for keeping energy; useless for spending it directly.

The currency

ATP

Small, soluble and immediately spendable. A typical cell turns over its own mass in ATP every day.

The rate

Seconds of supply

You hold only a few seconds' worth at any moment. Stop making it and the shortage is immediate.

ATPADP + PiHYDROLYSISreleases energyEXERGONICSYNTHESISrequires energyENDERGONIC−30.5 kJPER MOLEA CYCLE, NOT A STORE · TURNOVER IS MEASURED IN SECONDS
The reason a cell keeps so little ATP is that it does not need to. Hydrolysis and resynthesis run continuously in a tight loop, so ATP behaves like cash moving through a till rather than money in a vault. The same phosphate group may be attached and removed thousands of times a day.
Diagram · interactive

Inside the molecule

Tap each part. The instability is the feature, not a flaw — and it comes from charge, not from the bond itself.

ADENINERIBOSEPENTOSE SUGARPPTHE BOND THAT MATTERSPTERMINALTHREE NEGATIVE CHARGESCROWDED TOGETHERTAP A PART
Diagram

Adenine, ribose, three phosphates

Tap the base, the sugar, any of the three phosphates, the terminal bond, or the charge panel.

Signature interactive · CED 3.4

Paying for an uphill reaction

Five steps that turn an impossible reaction into a spontaneous one, without breaking any thermodynamics.

Concept 02 · CED 3.4

Which way will it go?

One sign decides everything. But it decides direction only — never speed, and never whether the reaction will happen this century.

ΔG < 0

Exergonic

Products hold less free energy than reactants. Energy is released and the reaction can proceed unaided.

ΔG > 0

Endergonic

Products hold more. Energy must be supplied from outside, and no enzyme can substitute for it.

The caveat

Spontaneous ≠ fast

Glucose oxidising in air is spontaneous, yet sugar keeps for years. Direction and rate are separate questions.

EXERGONICENDERGONICΔG < 0RELEASES ENERGYREACTANTSPRODUCTSΔG > 0REQUIRES ENERGYPRODUCTSREACTANTSSPONTANEOUS DOES NOT MEAN FAST
The dashed curve between the levels is the activation energy — and it exists in both diagrams. That is exactly why spontaneous does not mean fast, and why exergonic reactions in cells still need enzymes to happen at a useful rate.
Concept map · interactive

How it all hangs together

Tap a node to light up its connections. The pink dashed link is the rule that makes ATP necessary at all.

captured asreleased bymakeshydrolysedpowersoxidation ispays forneedsdrivesSunlightGlucoseRespirationATPHydrolysisCellular workExergonicCouplingEndergonic
Concept map

Tap a node

Follow the left column downward: sunlight to glucose to ATP to work.

Retrieval · drag and drop

Fill the gaps

Drag a term into a gap, or tap a term and then tap a gap. Two terms belong nowhere.

ATPexergonicendergoniccouplingphosphorylationhydrolysisspontaneousfree energy denaturationosmosis

The immediate energy currency of the cell is . A reaction with a negative change in is described as and is , whereas a reaction with a positive value is and will not proceed alone. Cells solve this by energy , in which the of ATP pays for the uphill reaction. Transferring the terminal phosphate group onto another molecule is called .

Check yourself · AP-style

Six questions

Single best answer. You get the reasoning as soon as you commit.