Biology  by Bradford
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IB Biology D1.3 Pub Quiz: Mutation and gene editing

D1.3 as a pub quiz for your class: review rounds on this subtopic, mixed with pure-fun rounds so it feels like a night out and not another test. Opens at SL; switch to HL in the builder to add the higher level cards.

Print teacher pagesPrint student pagesOpen in the builder to change it

Teacher pages are the quizmaster script and tally sheet. Student pages are the team answer sheet, handout and picture sheet. Both open ready to print, on A4 or US Letter.

What it covers

IB Biology at SL, with HL cards when you switch the level: D1.3 Mutation and gene editing.

The running order

nine rounds and a handout of riddles. Review rounds are drawn from this topic each time you open the quiz, so two classes never get the same paper, and every review round can be redrawn in a click.

  1. Riddle me this review
    Course terms as riddles: "I have a head that loves water and two tails that hate it…" Teams write what it is.
  2. Close-up fun
    A tiny zoomed-in patch. What's the full picture?
  3. Fact or fiction fun
    Myths and true-but-weird facts. Teams write Fact or Fiction.
  4. Think it through review
    Scenarios, odd ones out, true or false and why, puzzles: questions to reason through. Give teams a little longer.
  5. Films in science-speak fun
    A film plot, described like a research abstract. Name the film.
  6. Who am I? Scientists fun
    Three clues, hardest first. 3 points after clue 1, 2 after clue 2, 1 after clue 3.
  7. Missing vowels: course terms review
    Your key terms with the vowels taken out.
  8. Funny animal noises fun
    YouTube clips of animals making ridiculous noises. Screen off, listen, guess, then watch the reveal.
  9. Closest wins fun
    Estimation questions. Nearest team wins the point. Doubles as the tiebreaker.

A taste of the questions

Think it through

Scenarios, odd ones out and true or false and why, from IB Biology.

  1. Insert 1 base, delete 2 bases, insert 3 bases, delete 4 bases: which is the odd one out, leaving the reading frame intact?
  2. Why does a one-base insertion near the start of a gene usually do more harm than one near the end?
  3. A substitution hits one base of a codon. Which position is least likely to change the amino acid: first, second or third?
  4. A substitution changes an mRNA codon from UAC to UAA, a stop codon. What happens to the polypeptide?
  5. Why do years of sunbathing without protection raise the risk of skin cancer?
  6. True or false: with no radiation and no mutagenic chemicals, a cell would never mutate.
Answers
  1. Insert 3 bases (a whole codon; the others shift every codon after them)
  2. More codons lie after it (so more of the polypeptide is changed by the frameshift)
  3. The third (codons for one amino acid often differ only at the third base)
  4. It is cut short (translation stops early, so it probably doesn't work)
  5. UV is a mutagen (it damages the DNA of skin cells, causing mutations)
  6. False (errors in DNA replication or repair still cause mutations)

Riddle me this

Course terms as riddles. Teams write what it is.

  1. Add or lose a single letter and every codon after me is read out of step. What am I?
  2. I'm UV light, X-rays or a nasty chemical, and I alter the base sequence of your DNA. What am I?
  3. I'm a one-letter difference in DNA between people, left by an old substitution. Say my initials and I sound like a cut with scissors. What am I?
  4. One letter out, a different one in, and the gene is still exactly the same length. What am I?
  5. I happened in a lung cell, so I might cause cancer, but your children will never inherit me. What am I?
Answers
  1. A frameshift mutation
  2. A mutagen
  3. A single-nucleotide polymorphism (SNP)
  4. A base substitution
  5. A somatic mutation

Quickfire

Short recall from the same topics.

  1. Any change to the base sequence of DNA
  2. One nucleotide swapped for another
  3. Extra nucleotides added into a gene
Answers
  1. Mutation
  2. Base substitution
  3. Insertion

How it runs

  1. Open it in the builder. The running order loads ready to go. Swap, add or drop rounds, or draw a round's questions again.
  2. Present it or print it. Present puts each round on the projector in 16:9 with quizmaster notes. Print gives the script, team answer sheets, a picture sheet and a tally sheet on A4 or US Letter, with no projector needed.
  3. Score it. Teams swap sheets, mark, and each plays one joker to double a round. The scores page reveals the leaderboard from last place up.

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