Biology  by Bradford
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D3.3 Homeostasis: revision map

The subtopic in the middle and eleven tasks round it: label four diagrams, complete three tables, put two processes in order and fill 48 gaps. Every standard level statement has a box; the five boxes for higher level only are dashed and badged HL, and drop off for an SL class. Type into the blanks and check them, or print it on A4, Letter or A3 with an answer key.

D3.3 practice questionsThe whole D3 map

D3.3

Homeostasis

Organisms · Continuity and changeName

D3.3.3After a sugary meal

Number the steps in order.

  1. Insulin is carried in the blood to target cells all over the body.
  2. Liver and muscle cells take up glucose and store it as glycogen.
  3. Beta cells in the pancreas detect the rise and secrete insulin.
  4. Glucose absorbed from the gut raises blood glucose concentration.
  5. Blood glucose falls back to the set point, and insulin secretion falls.

When blood glucose falls too low, secrete , which makes liver cells break glycogen down to glucose.

D3.3.7, D3.3.9Two jobs of the kidneyHL

is the removal of waste products of metabolism, such as urea. is control of the osmotic concentration of body fluids, measured in osmol L⁻¹. In the loop of Henle, the ascending limb pumps out by , keeping the osmotic concentration of the medulla high so water can be reabsorbed from the collecting ducts.

D3.3.8, D3.3.9, D3.3.10Inside a nephronHL

12345
  1. 1
  2. 2
  3. 3
  4. 4
  5. 5

Blood pressure forces water and small solutes out of the plasma: . Then all the glucose and amino acids, and most of the water, are , leaving and other unwanted solutes to be excreted in urine.

D3.3 examA nephron and its collecting ductHL

A nephron and its collecting duct1234
  1. 1
  2. 2
  3. 3
  4. 4

D3.3.4Two types of diabetes

Type 1Type 2
Causethe immune system destroys the target cells become to insulin
Usual onsetchildhoodadulthood
Risk factorsinherited genes, inactivity, family history
Treatment or preventioninsulin injections, with blood glucose checksa healthy diet and , then drugs if needed

D3.3.5Temperature control loop

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  1. 1
  2. 2
  3. 3
  4. 4

The gland in the neck secretes , which raises the so body cells release more heat. Muscle and adipose tissue are , carrying out the response.

D3.3Homeostasis

D3.3.6Skin in heat and cold

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  1. 1
  2. 2
  3. 3

Birds and mammals regulate their temperature by physiological changes and by , such as seeking shade or huddling together.

D3.3.1, D3.3.2Keeping things steady

timelevel

Homeostasis keeps the within preset limits, whatever happens outside. In humans, body temperature, blood pH, blood glucose concentration and blood are all held near a . feedback brings a variable back whether it rises above or falls below; positive feedback would push it further away.

D3.3.6Too hot, too cold

EffectorResponse when too cold
Skin arterioles: less blood flows near the surface, so less heat is lost
Skeletal muscle: rapid contractions release heat from respiration
Brown adipose tissue: energy from respiration is released as heat instead of being used to make ATP
Hair erector musclescontract, so hairs stand up and trap a layer of insulating

When too hot, skin arterioles widen, , so more heat is lost from the blood at the surface, and sweat takes heat from the skin as it .

D3.3.10Short of waterHL

Number the steps in order.

  1. More water is reabsorbed by osmosis, leaving a small volume of concentrated urine.
  2. The pituitary gland secretes more ADH into the blood.
  3. Vesicles carrying aquaporins fuse with the cell membrane facing the filtrate.
  4. ADH binds to receptors on cells of the collecting duct.
  5. Osmoreceptors in the hypothalamus detect a rise in blood osmotic concentration.

With plenty of water, ADH secretion falls, the aquaporins are taken back into the cells, and a large volume of urine forms.

D3.3.11Where the blood goesHL

OrganBlood flow in vigorous exercise, compared with restReason
Skeletal musclesarterioles widen to bring oxygen and glucose for respiration
Gutarterioles narrow; digestion can wait
Kidneysarterioles narrow, sending blood to the muscles
Brainit must never be short of oxygen
Word bank active transportairalpha cellsarterioleascending limb of the loop of Henlebehaviourbeta cellsBowman's capsulecollecting ductdecreasesdiluteeffectorsevaporatesExcretionexerciseglomerulusglucagonhair erector musclehypothalamusincreasesinternal environmentloop of Henlemetabolic rateNegativeobesityOsmoregulationosmotic concentrationpituitary glandproximal convoluted tubulereabsorbedresistantset pointshiveringsodium ionsstays the samesweat glandthermoreceptorthyroid glandthyroxinultrafiltrationuncoupled respirationureavasoconstrictionvasodilation

Answer key

Every box on the sheet with its gaps filled in, as the subtopic reads in full.
  1. GapsKeeping things steady

    Homeostasis keeps the internal environment within preset limits, whatever happens outside. In humans, body temperature, blood pH, blood glucose concentration and blood osmotic concentration are all held near a set point. Negative feedback brings a variable back whether it rises above or falls below; positive feedback would push it further away.

  2. OrderAfter a sugary meal

    1. Glucose absorbed from the gut raises blood glucose concentration.
    2. Beta cells in the pancreas detect the rise and secrete insulin.
    3. Insulin is carried in the blood to target cells all over the body.
    4. Liver and muscle cells take up glucose and store it as glycogen.
    5. Blood glucose falls back to the set point, and insulin secretion falls.

    When blood glucose falls too low, alpha cells secrete glucagon, which makes liver cells break glycogen down to glucose.

  3. TableTwo types of diabetes

    Type 1Type 2
    Causethe immune system destroys the beta cellstarget cells become resistant to insulin
    Usual onsetchildhoodadulthood
    Risk factorsinherited genesobesity, inactivity, family history
    Treatment or preventioninsulin injections, with blood glucose checksa healthy diet and exercise, then drugs if needed
  4. LabelTemperature control loop

    1. thermoreceptor
    2. hypothalamus
    3. pituitary gland
    4. thyroid gland

    The gland in the neck secretes thyroxin, which raises the metabolic rate so body cells release more heat. Muscle and adipose tissue are effectors, carrying out the response.

  5. LabelSkin in heat and cold

    1. arteriole
    2. hair erector muscle
    3. sweat gland

    Birds and mammals regulate their temperature by physiological changes and by behaviour, such as seeking shade or huddling together.

  6. TableToo hot, too cold

    EffectorResponse when too cold
    Skin arteriolesvasoconstriction: less blood flows near the surface, so less heat is lost
    Skeletal muscleshivering: rapid contractions release heat from respiration
    Brown adipose tissueuncoupled respiration: energy from respiration is released as heat instead of being used to make ATP
    Hair erector musclescontract, so hairs stand up and trap a layer of insulating air

    When too hot, skin arterioles widen, vasodilation, so more heat is lost from the blood at the surface, and sweat takes heat from the skin as it evaporates.

  7. GapsTwo jobs of the kidney HL

    Excretion is the removal of waste products of metabolism, such as urea. Osmoregulation is control of the osmotic concentration of body fluids, measured in osmol L⁻¹. In the loop of Henle, the ascending limb pumps sodium ions out by active transport, keeping the osmotic concentration of the medulla high so water can be reabsorbed from the collecting ducts.

  8. LabelInside a nephron HL

    1. glomerulus
    2. Bowman's capsule
    3. proximal convoluted tubule
    4. loop of Henle
    5. collecting duct

    Blood pressure forces water and small solutes out of the plasma: ultrafiltration. Then all the glucose and amino acids, and most of the water, are reabsorbed, leaving urea and other unwanted solutes to be excreted in urine.

  9. OrderShort of water HL

    1. Osmoreceptors in the hypothalamus detect a rise in blood osmotic concentration.
    2. The pituitary gland secretes more ADH into the blood.
    3. ADH binds to receptors on cells of the collecting duct.
    4. Vesicles carrying aquaporins fuse with the cell membrane facing the filtrate.
    5. More water is reabsorbed by osmosis, leaving a small volume of concentrated urine.

    With plenty of water, ADH secretion falls, the aquaporins are taken back into the cells, and a large volume of dilute urine forms.

  10. TableWhere the blood goes HL

    OrganBlood flow in vigorous exercise, compared with restReason
    Skeletal musclesincreasesarterioles widen to bring oxygen and glucose for respiration
    Gutdecreasesarterioles narrow; digestion can wait
    Kidneysdecreasesarterioles narrow, sending blood to the muscles
    Brainstays the sameit must never be short of oxygen
  11. Exam diagramA nephron and its collecting duct HL

    1. glomerulus
    2. proximal convoluted tubule
    3. ascending limb of the loop of Henle
    4. collecting duct