Biology  by Bradford
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D1.3 Mutation and gene editing: grass skirts

17 quick questions on mutation and gene editing, 12 of them at standard level, each answered in a word or two. Print a sheet for each team, a key for the checker and a tick sheet, then tape the sheets to the board and race.

How it runs

  1. SnipA runner cuts one strip off the bottom of their team’s sheet.
  2. Answer as a pairBack at the table, they write the answer on the strip. No books.
  3. Get it checkedThe checker reads it against the key: you, or a student holding it.
  4. Back for the nextA tick earns the next strip. Wrong? Back to the table to try again.

The questions on this sheet

The checker’s key, with every answer, prints with the sheets.
  1. Any change to the base sequence of DNA
  2. One nucleotide swapped for another
  3. Extra nucleotides added into a gene
  4. Nucleotides lost from a gene
  5. Agent such as UV or X-rays that alters DNA
  6. Every codon after the change is misread
  7. One-base difference found in many people
  8. New codon, but no change in amino acid
  9. Change that creates an early stop codon
  10. DNA change in a gamete, so heritable
  11. DNA change in a body cell, not inherited
  12. Disabling one locus to find what it does
  13. Nuclease that cuts DNA at the guided site
  14. Molecule pairing with the DNA to be cut
  15. Region almost unchanged across species
  16. Site where base changes happen more often
  17. Bacterial DNA repeats storing viral memory

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