Biology  by Bradford
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Free · AP Biology · Unit 4

Cell Communication escape room

The Silent Relay Station

High on a frozen ridge, the Halvorsen relay station passes radio messages between distant valley towns. A blizzard has knocked out its main power, and the backup system has sealed every door until the crew proves it understands how signals are received, relayed and answered, just as cells do. Five locks stand between you and the snowcat outside, and each needs four answers decoded into a combination. Restore the signal before the storm closes in.

  • 5 locksfour multiple-choice questions at each, 20 in all
  • About 45 minutesfor a team of three or four
  • Online or on papera link to play, or the pack to print
  • ForAP Biology classes
  • Play linkbiologybybradford.com/escape/u4

The five locks

Each lock’s four answers are decoded with its puzzle into a four-digit combination, so one wrong answer keeps it shut. The questions climb from recall to evaluating evidence.
  1. Lock 1 · Recall

    Frosted Antenna Hatch

    Light panel Easy

    Add up the numbers above the shaded squares.

  2. Lock 2 · Understand

    Generator Room Door

    Bar chart Easy

    Each letter is a bar. Read its height off the scale.

  3. Lock 3 · Apply

    Radio Console Cabinet

    Petri dishes Medium

    Count only the solid colonies. Ignore the rings.

  4. Lock 4 · Analyse data

    Fuel Store Padlock

    Logic clues Medium

    A, B, C and D are four different digits. No clue gives a value away; combine them.

  5. Lock 5 · Evaluate

    Main Gate Transmitter

    Overlay Hard

    Panel 2 is upside down. Turn it round in your head; only segments lit on both panels count.

Lock 1, as a team sees it

The first four questions and their decoder. The answers, and the reason for each, are in the teacher pack.
  1. What is a signaling molecule that binds specifically to a receptor called?

    1. A Second messenger
    2. B Kinase
    3. C Cyclin
    4. D Ligand
  2. What is the term for the division of the nucleus?

    1. A Mitosis
    2. B Interphase
    3. C Cytokinesis
    4. D S phase
  3. What is programmed cell death, often triggered when a cell fails a checkpoint, called?

    1. A Necrosis
    2. B Apoptosis
    3. C Denaturation
    4. D Cytolysis
  4. Which mechanism maintains homeostasis by returning a variable to its set point?

    1. A Signal amplification
    2. B Negative feedback
    3. C Phosphorylation cascade
    4. D Positive feedback

Light panel

Easy

Add up the numbers above the shaded squares.

A
8421
B
8421
C
8421
D
8421

Running it

  1. Online: send teams the play link. They answer a lock’s four questions, decode the letters and enter the combination; after lock 5 they get a completion code to show you. Nobody needs an account.
  2. On paper: sign in (free) and print the teacher pack: question cards, the five decoders, a guide and the answer key with a reason for every answer.
  3. Your version: Edit a copy from the library to change any question, then play and print it by its own code, or build a room from the topics your class has covered.

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