3.5.A, 3.5.BRespiration in the cell
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The subtopic in the middle and five tasks round it: label a diagram, complete a table, put a process in order and fill 12 gaps. Every box rests on a learning objective of the topic in the AP Biology course and exam description. Type into the blanks and check them, or print it on A4, Letter or A3 with an answer key.
The carbon atoms of glucose are released as , mostly in pyruvate oxidation and the Krebs cycle, and the hydrogen ends up in water. Most ATP comes from the proton gradient rather than directly from the cycle itself, which is why a poison that blocks the electron transport chain stops nearly all ATP production.
| Stage | Where | Inputs | Main outputs |
|---|---|---|---|
| cytosol | glucose | 2 pyruvate, 2 ATP (net), 2 NADH | |
| Pyruvate oxidation | mitochondrial matrix | pyruvate | acetyl CoA, CO₂, NADH |
| mitochondrial matrix | acetyl CoA | CO₂, ATP, NADH, FADH₂ | |
| Oxidative phosphorylation | inner mitochondrial membrane | NADH, FADH₂, O₂ | , water |
Number the steps in order.
If oxygen is missing, the electron transport chain stops and NADH cannot be oxidized. Cells carry on with glycolysis, and regenerate NAD⁺ by . Animal cells reduce pyruvate to lactate, and yeast convert it to ethanol and CO₂. This gives only ATP per glucose, compared with about 30 to 32 from aerobic respiration, but it works quickly.
| Stage | Where | Inputs | Main outputs |
|---|---|---|---|
| Glycolysis | cytosol | glucose | 2 pyruvate, 2 ATP (net), 2 NADH |
| Pyruvate oxidation | mitochondrial matrix | pyruvate | acetyl CoA, CO₂, NADH |
| Krebs cycle | mitochondrial matrix | acetyl CoA | CO₂, ATP, NADH, FADH₂ |
| Oxidative phosphorylation | inner mitochondrial membrane | NADH, FADH₂, O₂ | ATP, water |
If oxygen is missing, the electron transport chain stops and NADH cannot be oxidized. Cells carry on with glycolysis, and regenerate NAD⁺ by fermentation. Animal cells reduce pyruvate to lactate, and yeast convert it to ethanol and CO₂. This gives only 2 ATP per glucose, compared with about 30 to 32 from aerobic respiration, but it works quickly.
The carbon atoms of glucose are released as carbon dioxide, mostly in pyruvate oxidation and the Krebs cycle, and the hydrogen ends up in water. Most ATP comes from the proton gradient rather than directly from the cycle itself, which is why a poison that blocks the electron transport chain stops nearly all ATP production.